Reproducibility and replicability of rodent phenotyping in preclinical studies

Show and tell: disclosure and data sharing in experimental pathology

Reproducibility of data from experimental investigations using animal models is increasingly under scrutiny because of the potentially negative impact of poor reproducibility on the translation of basic research. Histopathology is a key tool in biomedical research, in particular for the phenotyping of animal models to provide insights into the pathobiology of diseases. Failure to disclose and s...

NSF Reproducibility Framework 1 A Framework for Ongoing and Future National Science Foundation Activities to Improve Reproducibility, Replicability, and Robustness in Funded Research Prepared for the Office of Management and Budget

The confidence in and reliability of science and engineering research is truly invaluable and especially so at the National Science Foundation (NSF). Although outright fraud or falsification in science is rare, a number of factors can compromise the reproducibility of published studies in science and serving the public interest requires guarding against them. “Reproducibility”, “replicability” ...

Advancing Science with VGI: Reproducibility and Replicability of Recent Studies using VGI

Replicability is not Reproducibility: Nor is it Good Science

At various machine learning conferences, at various times, there have been discussions arising from the inability to replicate the experimental results published in a paper. There seems to be a wide spread view that we need to do something to address this problem, as it is essential to the advancement of our field. The most compelling argument would seem to be that reproducibility of experiment...

Replicability and Reproducibility in Comparative Psychology

Psychology faces a replication crisis. The Reproducibility Project: Psychology sought to replicate the effects of 100 psychology studies. Though 97% of the original studies produced statistically significant results, only 36% of the replication studies did so (Open Science Collaboration, 2015). This inability to replicate previously published results, however, is not limited to psychology (Ioan...